To everyone who supported and collaborated with Nexleaf in 2025: Thank you! Here are some of our highlights from the year.
Connecting 30,700+ Clinics in 36 Countries
Nexleaf’s equipment management solution now connects more than 30,700 last mile clinics, district stores, and regional hospitals across Africa and Asia.
Each ColdTrace device operationalizes dozens of data points per refrigerator per day, enabling health teams to detect failures early, prioritize maintenance, and prevent vaccine loss before it happens. The result is a vaccine cold chain that is monitored, actionable, and accountable – every day, not just during audits.
As Nexleaf CEO & Co-Founder Nithya Ramanathan and Board member Jim Fruchterman argue in Gather, Share, Build, accurate and abundant data is a crucial resource. We need data at scale to ensure everyone benefits from the emerging power of AI.
17,000+ Health Workers Receiving Alerts
More than 17,000 frontline health workers around the world receive real-time alerts from Nexleaf devices when key equipment is failing – turning data into action.
Through the Gavi-supported Rapid Response & Repair (R3) initiative, Nexleaf pairs this visibility with clear workflows, tools, and accountability, enabling Ministries of Health to move from reactive to proactive equipment management. Insights from users feed directly back into the platform, inspiring new features that continuously improve immunization system performance nation-wide.
86M+ Children & $5B+ in Vaccines Protected
When the vaccine cold chain works well, even the hardest-to-reach children have access to potent, effective vaccines. Since 2022, Nexleaf tech has protected the vaccine supply for over 86 million children and has safeguarded over $5 billion in vaccine investments by reducing equipment failure and preventable loss.
Innovating Operational AI
Nexleaf is applying AI where it delivers immediate value: the operation and maintenance of health infrastructure. Early deployment evidence shows frontline users actively querying equipment data, and following up with requests for repair guidance through the platform. This use case for Operational AI reduces dependence on – and the cost of – repeat in-person training while extending expert support to the last mile at scale.
Nexleafers Around the World
Our global team is distributed across 10 countries. Nexleaf’s Country Managers in Tanzania, Malawi, Rwanda, and Pakistan partner directly with Ministries of Health and government representatives to ensure sustained country ownership. Our engineers, product managers, and manufacturing team members in Kenya, Thailand, and India work ceaselessly behind the scenes to keep the system working and delivering value for our customers
Our team was also out in full force at key events and conferences throughout this pivotal year. In addition to the Gavi Global Summit and UNGA, the Skoll Forum, and the World Health Assembly, Nexleaf presented at the Global Digital Health Forum, the Global Health Supply Chain Summit, and CPHIA, and represented at the Africa HealthTech Summit and Africa Health ExCon.
A Note from Our CEO and Co-Founder
In 2025, we saw seismic change in both the global health and technology sectors. As a leader, I’ve been moved by the resilience and fortitude, not only from my team and our partners, but from everyone who remains dedicated to alleviating inequities and improving healthcare access for all. Chaotic upheaval is hard, but I am hopeful we can seize the moment to bring about long-overdue changes. Local sovereignty and control – including control of data and country-led interventions to strengthen health systems – are required for sustainable improvements in health outcomes.
As we look forward to 2026, let’s continue building together, closing the healthcare access gap and the digital divide, and equipping health workers around the world with the data and resources they need to save lives.
-Nithya